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3,531 questions
Which of the following is the most common characteristic of a serous cystadenocarcinoma of the ovary?
A 31/2-year-old female presented with a left upper quadrant abdominal mass. The child had no previous history of medical illnesses. An ultrasound examination revealed a markedly deformed left kidney with 12 cm nonhomogenous soft tissue mass arising from the upper pole. Medial displacement of the bowel loops was also noted. What is the survival rate of this tumor with chemotherapy, radiation therapy, and surgery?
A 23-year-old female sought medical help because of a painless asymmetrical enlargement of the lower neck. The patient had no history of dyspnea, dysphagia, hoarseness, or previous radiation exposure. On physical examination, besides the enlarged asymmetrical thyroid gland, there was also a palpable lymphadenopathy. A lymph node biopsysee Figure, was performed. Hematoxilin and eosin (H&E) stained slide shows the lesion. What are the typical nuclear findings of this tumor?
A 60-year-old male is evaluated following a pathologic fracture of his humerus. As part of the workup, a bone biopsy is performed and the photomicrograph is shown in Figure below Which of the following is the most likely diagnosis?
A 23-year-old female graduate student with acne and asthma presents to you with a chief complaint of headaches. She has noted a gradual increase in the intensity and frequency of the headaches to the point where they are interfering with her daily activities and studies. Your examination shows an obese young lady with papilledema. The remainder of your physical examination is normal The test ordered above was negative. Which of the following is your most appropriate next step?
Amiddle-aged female presents with a painless enlargement of the lower aspect of the neck. With appropriate testing this is proven to be thyroid enlargement. Thyroid function tests were normal. Asurgical intervention was performed for diagnostic purposes. Figure below depicts a representative area of how most of thethyroid gland histologic features were seen. What are the clinical thyroid function test characteristics of the last stages of this disease?
Polyarteritis nodosa (PAN) typically involves which of the following?
The most likely cause of the pathologic findings in the spleen shown in Figure below is which of the following?
A 72-year-old male presented with nonspecific symptoms of easy fatigability, weight loss, and anorexia. On physical examination, generalized lymphadenopathy and hepatosplenomegaly were present. On the peripheral blood, he was found to have a marked lymphocytosis and in the serum, a small monoclonal spike was present. This disease is most prevalent in which age group?
A 42-year-old man presents to your clinic with a 1-week history of pain and inflammation involving his right first metatarsophalangeal (MTP) joint. He describes the pain as sudden in onset and worse at night. He denies experiencing any fever or traumatic injury to the joint and states that he has never had this type of pain before. He denies any chronic medical conditions, any prior surgery, and any current medication use. Besides an erythematous and exquisitely tender right first MTP joint, the remainder of his physical examination is unremarkable. What is a potential long-term complication of this patient's condition?
Which of the following patients is most likely to progress to develop cirrhosis?
A 72-year-old male presented with nonspecific symptoms of easy fatigability, weight loss, and anorexia. On physical examination, generalized lymphadenopathy and hepatosplenomegaly were present. On the peripheral blood, he was found to have a marked lymphocytosis and in the serum, a small monoclonal spike was present. The clinical behavior of this disease can best be described by which of the following?
An autopsy is performed on an 82-year-old female diagnosed with Alzheimer disease. Which of the following is most likely to be found on evaluation of her brain?
You are following up in your office with a patient who had a magnetic resonance imaging (MRI) of his head for evaluation of persistent headaches. The MRI report reveals a mass suspicious for malignancy. While explaining the need for ongoing testing to determine the etiology, the patient's spouse asks you, "What is the most common tumor in the brain?" Which of the following would be the correct response to this question?
A 42-year-old man presents to your clinic with a 1-week history of pain and inflammation involving his right first metatarsophalangeal (MTP) joint. He describes the pain as sudden in onset and worse at night. He denies experiencing any fever or traumatic injury to the joint and states that he has never had this type of pain before. He denies any chronic medical conditions, any prior surgery, and any current medication use. Besides an erythematous and exquisitely tender right first MTP joint, the remainder of his physical examination is unremarkable. After 1 week of treatment, your patient states that his pain and inflammation have resolved. You measure a serum urate level and find it elevated. Urinary urate excretion is high. Which of the following interventions is now most appropriate?
A 25-year-old female presents for evaluation of a breast mass and tenderness. She describes the breast soreness as varying with her menstrual cycles. On examination, you feel a firm, movable, irregular 2 cm mass. Her breast tissue is diffusely dense bilaterally. Of the options listed, which is the most likely?
A 45-year-old woman presents with a slowly growing mass near the right jaw. You palpate a firm nodule in the parotid gland but find no adenopathy and no other abnormality on examination. A biopsy reveals both epithelial and stromal elements. What is this patient's diagnosis?
A 60-year-old male developed painless hematuria. On further clinical evaluation, a CT scan showed a 7 cm mass on the lower pole of the right kidney. What would be your most likely diagnosis in this case?
A 28-year-old male undergoes an orchiectomy because of a suspicious testicular mass. The pathologic evaluation reveals the tumor to have gross and microscopic hemorrhage and necrosis. The tumor is noted to be composed mostly of cytotrophoblastic and syncytiotrophoblastic cells. What is this patient's diagnosis?
An 18-year-old male developed chills, fever, and a painful swollen knee. What test would be most appropriate in order to help in making the diagnosis?